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Article

Linezolid resistance in patients with drug-resistant TB and treatment failure in South Africa

16 Apr 2019

Abstract excerpt

OBJECTIVES: Limited data exist on clinical associations and genotypic correlates of linezolid resistance in Mycobacterium tuberculosis. We aimed to describe mutations and clinical factors associated with phenotypic linezolid resistance from patients with drug-resistant TB at two public sector facilities in South Africa. METHODS: Adults and adolescents with treatment failure (culture positivity ≥4 months) on a...

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PMID: 31081017
DOI: 10.1093/jac/dkz206

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