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Article

Alterations in DNA Damage Repair Genes in Primary Liver Cancer

8 May 2019

Abstract excerpt

Abstract Purpose: Alterations in DNA damage repair (DDR) genes produce therapeutic biomarkers. However, the characteristics and significance of DDR alterations remain undefined in primary liver cancer (PLC). Experimental Design: Patients diagnosed with PLC were enrolled in the trial (PTHBC, NCT02715089). Tumors and matched blood samples from participants were collected for a targeted next-generation sequencing...

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PMID: 31068370
DOI: 10.1158/1078-0432.ccr-19-0127

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