Impact of the HOTAIR (rs920778) and miR-3117 (rs7512692) variants on the Susceptibility and Clinicopathologic characteristics of patients with colorectal cancer

Abstract excerpt

<title>Abstract</title><p><bold>Background</bold>: Colorectal cancer (CRC) is the most common type of gastrointestinal cancer. Genetic, epigenetic, and lifestyle factors have been implicated in the development of CRC. Non-coding RNAs such as HOX transcript antisense RNA (<italic>HOTAIR</italic>) and<italic>miR-3117</italic>genes have been associated with cell proliferation, progression, invasion, and metastasis as...

Topics

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• Aged
• Case-Control Studies
• Colorectal Neoplasms
• Haplotypes
• Odds Ratio
• Polymorphism, Single Nucleotide
• Risk
• RNA, Long Noncoding

Identifiers and source

Literature Corpus work

eeae3fb8-2c8f-5ebc-b9e4-283dc10a06e2

DOI

10.21203/rs.3.rs-4421174/v1