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Article

MGMT -535G>T polymorphism is associated with prognosis for patients with metastatic colorectal cancer treated with oxaliplatin-based chemotherapy.

Journal of cancer research and clinical oncology - 1 Aug 2010

Park Jee Hyun, Kim Nung Soo, Park Jae Yong, Chae Yee Soo, Kim Jong Gwang, Sohn Sang Kyun, Moon Joon Ho, Kang Byung Woog, Ryoo Hun Mo, Bae Sung Hwa, Choi Gyu Seog, Jun Soo-Han

Abstract excerpt

PURPOSE: The present study analyzed the polymorphisms of DNA repair genes and their impact on the response to chemotherapy and survival of patients with colorectal cancer. PATIENTS AND METHODS: A total of 94 patients with recurrent or metastatic colorectal cancer treated with oxaliplatin-based combination chemotherapy were enrolled in the present study. The single nucleotide polymorphisms of 16 DNA repair genes...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 20091185
DOI: 10.1007/s00432-010-0760-8

Genes

MGMT
MSH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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