Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic variations in microRNA-binding sites of solute carrier transporter genes as predictors of clinical outcome in colorectal cancer.

Carcinogenesis - 17 Apr 2021

Bendova Petra, Pardini Barbara, Susova Simona, Rosendorf Jachym, Levy Miloslav, Skrobanek Pavel, Buchler Tomas, Kral Jan, Liska Vaclav, Vodickova Ludmila, Landi Stefano, Soucek Pavel, Naccarati Alessio, Vodicka Pavel, Vymetalkova Veronika

Abstract excerpt

One of the principal mechanisms of chemotherapy resistance in highly frequent solid tumors, such as colorectal cancer (CRC), is the decreased activity of drug transport into tumor cells due to low expression of important membrane proteins, such as solute carrier (SLC) transporters. Sequence complementarity is a major determinant for target gene recognition by microRNAs (miRNAs). Single-nucleotide polymorphisms...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 3' Untranslated Regions
Share to Chemotherapy, Adjuvant

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Colorectal Neoplasms

Share to MicroRNAs

Share to Neoplasm Recurrence, Local

Share to Organic Anion Transporters

Share to Organic Cation Transport Proteins

Share to Organic Cation Transporter 2

Source

Identifiers

PMID: 33319241
DOI: 10.1093/carcin/bgaa136

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic variations in microRNA-binding sites of solute carrier transporter genes as predictors of clinical outcome in colorectal cancer.PMID 33319241Read ↗

mirSNPs as Potential Colorectal Cancer Biomarkers: A Systematic ReviewSemantic proximity Read ↗

Prediction of the biological effect of polymorphisms within microRNA binding sites.Semantic proximity Read ↗

Single nucleotide polymorphisms in microRNA binding sites: implications in colorectal cancer.Semantic proximity Read ↗

mirSNPs as Potential Colorectal Cancer Biomarkers: A Systematic Review.Semantic proximity Read ↗

Polymorphisms in Non-coding RNA Genes and Their Targets Sites as Risk Factors of Sporadic Colorectal Cancer.Semantic proximity Read ↗

Polymorphisms in MicroRNA Binding Sites Predict Colorectal Cancer Survival.Semantic proximity Read ↗

Role of miRNA gene variants in the susceptibility and pharmacogenetics of colorectal cancer.Semantic proximity Read ↗

Polymorphisms in microRNA binding sites of mucin genes as predictors of clinical outcome in colorectal cancer patients.Semantic proximity Read ↗

Variation within 3'-UTRs of base excision repair genes and response to therapy in colorectal cancer patients: A potential modulation of microRNAs binding.Semantic proximity Read ↗

SNPs in microRNA binding sites as prognostic and predictive cancer biomarkers.Semantic proximity Read ↗

Genetic variation in microRNA-binding site and prognosis of patients with colorectal cancer.Semantic proximity Read ↗

Genetic polymorphisms in pre-microRNA genes as prognostic markers of colorectal cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.