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Article

Genetic Variants of HOTAIR Associated with Colorectal Cancer: A Case-Control Study in the Saudi Population.

Genes - 26 Feb 2023

Alzeer Haya Saad, Shaik Jilani P, Reddy Parine Narasimha, Alanazi Mohammad, Alamri Abdullah Al, Bhat Ramesa Shafi, Daihan Sooad Al

Abstract excerpt

Genetic polymorphism in long noncoding RNA (lncRNA) HOTAIR is linked with the risk and susceptibility of various cancers in humans. The mechanism involved in the development of CRC is not fully understood but single nucleotide polymorphisms (SNPs) can be used to predict its risk and prognosis. In the present case-control study, we investigated the relationship between HOTAIR (rs12826786, rs920778, and rs1899663)...

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Identifiers

PMID: 36980864
DOI: 10.3390/genes14030592
PMCID: PMC10047939

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