Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

DNA alteration‐based classification of uveal melanoma gives better prognostic stratification than immune infiltration, which has a neutral effect in high‐risk group

25 Apr 2019

Abstract excerpt

BACKGROUND: In uveal melanomas, immune infiltration is a marker of poor prognosis. This work intended to decipher the biological characteristics of intra-tumor immune population, compare it to other established biomarkers and to patients' outcome. METHODS: Primary, untreated, and mainly large uveal melanomas with retinal detachment were analyzed using: transcriptomic profiling (n = 15), RT-qPCR (n = 36),...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Ocular Disorders and Treatments
Share to Ocular Oncology and Treatments
Share to Veterinary Oncology Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 31025552
DOI: 10.1002/cam4.2122

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

DNA alteration‐based classification of uveal melanoma gives better prognostic stratification than immune infiltration, which has a neutral effect in high‐risk groupPMID 31025552Read ↗

Identification of a novel immune-related gene signature for prognosis and the tumor microenvironment in patients with uveal melanoma combining single-cell and bulk sequencing dataSemantic proximity Read ↗

Immunological analyses reveal an immune subtype of uveal melanoma with a poor prognosis.Semantic proximity Read ↗

Identification of an Immune-Related Prognostic Signature Associated With Immune Infiltration in MelanomaSemantic proximity Read ↗

Gene Expression Profiling in Uveal Melanoma Reveals Two Molecular Classes and Predicts Metastatic DeathSemantic proximity Read ↗

Identification of an Immune-Related Prognostic Signature Associated with Immune Infiltration in MelanomaSemantic proximity Read ↗

Machine Learning-based Classifier to Decipher Immune Landscape of Uveal Melanoma and Predict Patient OutcomesSemantic proximity Read ↗

Construction of a Promising Tumor-Infiltrating CD8+ T Cells Gene Signature to Improve Prediction of the Prognosis and Immune Response of Uveal MelanomaSemantic proximity Read ↗

Single-cell and bulk transcriptome analysis reveals tumor cell heterogeneity and underlying molecular program in uveal melanomaSemantic proximity Read ↗

Genetic evolution of uveal melanoma guides the development of an inflammatory microenvironment.Semantic proximity Read ↗

Heterogeneity revealed by integrated genomic analysis uncovers a molecular switch in malignant uveal melanoma.Semantic proximity Read ↗

Identification of Immune Cell Infiltration Landscape and Their Prognostic Significance in Uveal MelanomaSemantic proximity Read ↗

DNA methylation aberrancy is a reliable prognostic tool in uveal melanomaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.