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Article

High Expression of Glycolytic Genes in Clinical Glioblastoma Patients Correlates with Lower Survival

2021-10-08

Abstract excerpt

Glioblastoma (GBM), the most aggressive brain tumor, is associated with a median survival at diagnosis of 16-20 months and limited treatment options. The key hallmark of GBM is altered tumor metabolism and marked increase in the rate of glycolysis. Aerobic glycolysis along with elevated glucose consumption and lactate production supports rapid cell proliferation and GBM growth. In this study, we examined the gene...

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Literature Corpus work
d6a97b33-6e40-54aa-baf4-87e038fc11d8
DOI
10.1101/2021.10.07.463555
Open publication

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High Expression of Glycolytic Genes in Clinical Glioblastoma Patients Correlates with Lower SurvivalDOI 10.1101/2021.10.07.463555
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