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Article

Micromanaging aerobic respiration and glycolysis in cancer cells

5 Feb 2019

Abstract excerpt

BACKGROUND: Cancer cells possess a common metabolic phenotype, rewiring their metabolic pathways from mitochondrial oxidative phosphorylation to aerobic glycolysis and anabolic circuits, to support the energetic and biosynthetic requirements of continuous proliferation and migration. While, over the past decade, molecular and cellular studies have clearly highlighted the association of oncogenes and tumor...

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Identifiers

PMID: 30837197
DOI: 10.1016/j.molmet.2019.01.014

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