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Article

Ceramides in Parkinson’s Disease: From Recent Evidence to New Hypotheses

2 Apr 2019

Abstract excerpt

Ceramides (Cer) constitute a class of lipids present in the cell membranes where they act as structural components, but they can also work as signaling molecules. Increasing genetic and biochemical evidence supports a link between deregulation of ceramide metabolism in the brain and neurodegeneration. Here, we provide an overview of the genes and cellular pathways that link Cer with Parkinson's disease and...

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PMID: 31001082
DOI: 10.3389/fnins.2019.00330

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