Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Gene-Environment-Time Interactions in Neurodegenerative Diseases: Hypotheses and Research Approaches

1 Jan 2018

Abstract excerpt

BACKGROUND: Amyotrophic lateral sclerosis (ALS), Alzheimer's, and Parkinson's diseases are age-related neurodegenerative diseases. ALS is not a single entity but a syndrome with many different causes. In all 3 diseases, gene mutations account for only 10-15% of cases. Many environmental and lifestyle factors have been implicated as risk factors for ALS, though none have been proven to cause the disease. It is...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amyotrophic Lateral Sclerosis Research
Share to Bioinformatics and Genomic Networks
Share to Genetic Neurodegenerative Diseases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 31000966
DOI: 10.1159/000495321

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Gene-Environment-Time Interactions in Neurodegenerative Diseases: Hypotheses and Research ApproachesPMID 31000966Read ↗

The amyotrophic lateral sclerosis exposome: recent advances and future directions.Semantic proximity Read ↗

Unraveling the complex interplay between genes, environment, and climate in ALS.Semantic proximity Read ↗

Genes and the environment in neurodegeneration.Semantic proximity Read ↗

Emerging insights into the complex genetics and pathophysiology of amyotrophic lateral sclerosis.Semantic proximity Read ↗

Amyotrophic lateral sclerosis: translating genetic discoveries into therapies.Semantic proximity Read ↗

Genetics meets environment: evaluating gene-environment interactions in neurologic diseases.Semantic proximity Read ↗

The biological pathways of Alzheimer disease: a reviewSemantic proximity Read ↗

Identification of risk factors associated with onset and progression of amyotrophic lateral sclerosis using systematic review and meta-analysis.Semantic proximity Read ↗

What causes amyotrophic lateral sclerosis?Semantic proximity Read ↗

Neuroinflammation represents a common theme amongst genetic and environmental risk factors for Alzheimer and Parkinson diseasesSemantic proximity Read ↗

Pharmacogenomics of neurodegenerative diseases.Semantic proximity Read ↗

Environmental factors in the development and progression of late-onset Alzheimer’s diseaseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.