Article
Pharmacogenomics of neurodegenerative diseases.
European journal of pharmacology - 9 Feb 2001
Maimone D, Dominici R, Grimaldi L M
Abstract excerpt
Current knowledge of sporadic degenerative disorders suggests that, despite their multifactorial etiopathogenesis, genetics plays a primary role in orchestrating the pathological events, and even dramatically changes the disease phenotype from patient to patient. Genes may act as susceptibility factors, increasing the risk of disease development, or may operate as regulatory factors, modulating the magnitude and...
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