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Endothelial cell-derived nidogen-1 inhibits migration of SK-BR-3 breast cancer cells

4 Apr 2019

Abstract excerpt

BACKGROUND: The tumour microenvironment is a critical regulator of malignant cancer progression. While endothelial cells have been widely studied in the context of tumour angiogenesis, their role as modulators of cancer cell invasion and migration is poorly understood. METHODS: We have investigated the influence of endothelial cells on the invasive and migratory behaviour of human cancer cells in vitro. RESULTS:...

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PMID: 30947697
DOI: 10.1186/s12885-019-5521-8

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