Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cleavage of galectin-3 by matrix metalloproteases induces angiogenesis in breast cancer.

International journal of cancer - 1 Dec 2010

Nangia-Makker Pratima, Wang Yi, Raz Tirza, Tait Larry, Balan Vitaly, Hogan Victor, Raz Avraham

Abstract excerpt

Galectin-3 cleavage is related to progression of human breast and prostate cancer and is partly responsible for tumor growth, angiogenesis and apoptosis resistance in mouse models. A functional polymorphism in galectin-3 gene, determining its susceptibility to cleavage by matrix metalloproteinases (MMPs)-2/-9 is related to racial disparity in breast cancer incidence in Asian and Caucasian women. The purpose of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Growth Processes
Share to Chemotaxis

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Coculture Techniques

Share to Endothelial Cells

Share to Galectin 3

Share to Matrix Metalloproteinase 2

Share to Matrix Metalloproteinase 9

Share to Neovascularization, Pathologic

Source

Open in PubMed Open full text

Identifiers

PMID: 20162566
DOI: 10.1002/ijc.25254
PMCID: PMC3334857

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cleavage of galectin-3 by matrix metalloproteases induces angiogenesis in breast cancer.PMID 20162566Read ↗

Galectin-3: A novel substrate for c-Abl kinase.Semantic proximity Read ↗

Down-regulation of galectin-3 suppresses tumorigenicity of human breast carcinoma cells.Semantic proximity Read ↗

Pattern Analysis of Galectin 1, 3, and 9 Serum Levels in Breast CancerSemantic proximity Read ↗

Galectin-3 coats the membrane of breast cells and makes a signature of tumours.Semantic proximity Read ↗

Galectin-9 signaling drives breast cancer invasion through matrixSemantic proximity Read ↗

Matrix Metallopeptidase 3 Polymorphisms: Emerging genetic Markers in Human Breast Cancer MetastasisSemantic proximity Read ↗

Full-Length Semaphorin-3C Is an Inhibitor of Tumor Lymphangiogenesis and MetastasisSemantic proximity Read ↗

Racial disparity in breast cancer and functional germ line mutation in galectin-3 (rs4644): a pilot study.Semantic proximity Read ↗

The COOH-terminal globular domain of fibrinogen gamma chain suppresses angiogenesis and tumor growth.Semantic proximity Read ↗

The alpha 3 beta 1 integrin is associated with mammary carcinoma cell metastasis, invasion, and gelatinase B (MMP-9) activity.Semantic proximity Read ↗

Endothelial cell-derived nidogen-1 inhibits migration of SK-BR-3 breast cancer cellsSemantic proximity Read ↗

A galectin-3 sequence polymorphism confers TRAIL sensitivity to human breast cancer cells.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.