Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Circulating Cell-Free DNA and RNA Analysis as Liquid Biopsy: Optimal Centrifugation Protocol

30 Mar 2019

Abstract excerpt

The combined analysis of circulating cell-free (tumor) DNA (cfDNA/ctDNA) and circulating cell-free (tumor) RNA (cfRNA/ctRNA) shows great promise in determining the molecular profile of cancer patients. Optimization of the workflow is necessary to achieve consistent and reproducible results. In this study, we compared five centrifugation protocols for the optimal yield of both cfDNA/ctDNA and cfRNA/ctRNA. These...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Genomics and Diagnostics
Share to Pancreatic and Hepatic Oncology Research
Share to Single-cell and spatial transcriptomics

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 30935089
DOI: 10.3390/cancers11040458

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Circulating Cell-Free DNA and RNA Analysis as Liquid Biopsy: Optimal Centrifugation ProtocolPMID 30935089Read ↗

Optimization of Sources of Circulating Cell-Free DNA Variability for Downstream Molecular Analysis.Semantic proximity Read ↗

Circulating Cell-Free DNA Yield and Circulating-Tumor DNA Quantity from Liquid Biopsies of 12 139 Cancer Patients.Semantic proximity Read ↗

Liquid biopsy and PCR-free ultrasensitive detection systems in oncology (Review).Semantic proximity Read ↗

A Study of Pre-Analytical Variables and Optimization of Extraction Method for Circulating Tumor DNA Measurements by Digital Droplet PCRSemantic proximity Read ↗

Pre-analytical optimization of cell-free DNA and extracellular vesicle-derived DNA for mutation detection in liquid biopsies.Semantic proximity Read ↗

Evaluation of automatic cell free DNA extraction metrics using different blood collection tubesSemantic proximity Read ↗

Effects of Collection and Processing Procedures on Plasma Circulating Cell-Free DNA from Cancer Patients.Semantic proximity Read ↗

Comparison of methods for circulating cell-free DNA isolation using blood from cancer patients: impact on biomarker testingSemantic proximity Read ↗

Preanalytical blood sample workup for cell-free DNA analysis using Droplet Digital PCR for future molecular cancer diagnostics.Semantic proximity Read ↗

Comparative Liquid Biopsy Testing for KRAS Mutations From Plasma Cell-Free DNA (cfDNA) and Extracellular Vesicles in Lung Adenocarcinoma.Semantic proximity Read ↗

Comparison of Circulating Cell-Free DNA Extraction Methods for Downstream Analysis in Cancer PatientsSemantic proximity Read ↗

Plasma vs. serum in circulating tumor DNA measurement: characterization by DNA fragment sizing and digital droplet polymerase chain reaction.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.