Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Evidence of causal effect of major depression on alcohol dependence: findings from the psychiatric genomics consortium

1 Apr 2019

Abstract excerpt

BACKGROUND: Despite established clinical associations among major depression (MD), alcohol dependence (AD), and alcohol consumption (AC), the nature of the causal relationship between them is not completely understood. We leveraged genome-wide data from the Psychiatric Genomics Consortium (PGC) and UK Biobank to test for the presence of shared genetic mechanisms and causal relationships among MD, AD, and AC....

Topics

Join the communities discussing this publication.

Alcohol Consumption and Health Effects
Genetic Associations and Epidemiology
Substance Abuse Treatment and Outcomes

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 30929657
DOI: 10.1017/s0033291719000667

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Evidence of causal effect of major depression on alcohol dependence: findings from the psychiatric genomics consortiumPMID 30929657Read ↗

Evidence of causal effect of major depression on alcohol dependence: Findings from the Psychiatric Genomics ConsortiumSemantic proximity Read ↗

Shared genetic etiology between alcohol dependence and major depressive disorder.Semantic proximity Read ↗

Polygenic Scores for Major Depressive Disorder and Risk of Alcohol Dependence.Semantic proximity Read ↗

Transancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders.Semantic proximity Read ↗

Genetic Risk Variants Associated With Comorbid Alcohol Dependence and Major Depression.Semantic proximity Read ↗

Genome-wide association study of alcohol dependence:significant findings in African- and European-Americans including novel risk loci.Semantic proximity Read ↗

Phenome-wide investigation of bidirectional causal relationships between major depressive disorder and common human diseases.Semantic proximity Read ↗

Shared additive genetic influences on DSM-IV criteria for alcohol dependence in subjects of European ancestry.Semantic proximity Read ↗

Genome-wide association study of comorbid depressive syndrome and alcohol dependence.Semantic proximity Read ↗

A Genome-Wide Association Study Reveals New Genes in a Molecular Network Associated With Alcohol Dependence and Related Clinical MeasuresSemantic proximity Read ↗

The genetics of alcohol dependence: Twin and SNP-based heritability, and genome-wide association study based on AUDIT scores.Semantic proximity Read ↗

Alcohol Use and Depression: A Mendelian Randomization Study From ChinaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.