Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Treatment of Chronic Hepatitis B Virus Infection Using Small Molecule Modulators of Nucleocapsid Assembly: Recent Advances and Perspectives

21 Mar 2019

Abstract excerpt

On the basis of the recent advance of basic research on molecular biology of hepatitis B virus (HBV) infection, novel antiviral drugs targeting various steps of the HBV life cycle have been developed in recent years. HBV nucleocapsid assembly is now recognized as a hot target for anti-HBV drug development. Structural and functional analysis of HBV nucleocapsid allowed rational design and improvement of small...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Hepatitis B Virus Studies
Share to Hepatitis C virus research
Share to HIV/AIDS drug development and treatment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 30896149
DOI: 10.1021/acsinfecdis.8b00337

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Treatment of Chronic Hepatitis B Virus Infection Using Small Molecule Modulators of Nucleocapsid Assembly: Recent Advances and PerspectivesPMID 30896149Read ↗

The Hepatitis B Virus Nucleocapsid—Dynamic Compartment for Infectious Virus Production and New Antiviral TargetSemantic proximity Read ↗

Novel non-HAP class A HBV capsid assembly modulators have distinct in vitro and in vivo profilesSemantic proximity Read ↗

Current Status and Challenges in Anti-Hepatitis B Virus Agents Based on Inactivation/Inhibition or Elimination of Hepatitis B Virus Covalently Closed Circular DNASemantic proximity Read ↗

Targeting the Achilles heel of the hepatitis B virus: a review of current treatments against covalently closed circular DNA.Semantic proximity Read ↗

Inhibition of hepatitis B virus replication by drug-induced depletion of nucleocapsids.Semantic proximity Read ↗

Synthesis and Evaluation of N-Phenyl-3-sulfamoyl-benzamide Derivatives as Capsid Assembly Modulators Inhibiting Hepatitis B Virus (HBV).Semantic proximity Read ↗

Preclinical and clinical antiviral characterization of AB-836, a potent capsid assembly modulator against hepatitis B virus.Semantic proximity Read ↗

Nucleoside Inhibitors of Hepatitis C Virus NS5B Polymerase: A Systematic Review.Semantic proximity Read ↗

Dysregulation of Hepatitis B Virus Nucleocapsid Assembly with RNA-directed Small LigandsSemantic proximity Read ↗

RNA Interference Therapeutics for Chronic Hepatitis B: Progress, Challenges, and Future ProspectsSemantic proximity Read ↗

The progress of molecules and strategies for the treatment of HBV infectionSemantic proximity Read ↗

In vitro inhibition of HBV replication by a novel compound, GLS4, and its efficacy against adefovir-dipivoxil-resistant HBV mutations.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.