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Article

Role of the global regulator Rex in control of NAD+‐regeneration in Clostridioides (Clostridium) difficile

18 Mar 2019

Abstract excerpt

Summary For the human pathogen Clostridioides (also known as Clostridium) difficile, the ability to adapt to nutrient availability is critical for its proliferation and production of toxins during infection. Synthesis of the toxins is regulated by the availability of certain carbon sources, fermentation products and amino acids (e.g. proline, cysteine, isoleucine, leucine and valine). The effect of proline is...

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PMID: 30882947
DOI: 10.1111/mmi.14245

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