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Article

IRF2–INPP4B-mediated autophagy suppresses apoptosis in acute myeloid leukemia cells

15 Mar 2019

Abstract excerpt

BACKGROUND: The present study aimed to investigate the underlying role of interferon-regulatory factor 2 (IRF2)-inositol polyphosphate-4-phosphatase, type-II (INPP4B) axis in the regulation of autophagy in acute myeloid leukemia (AML) cells. METHODS: Quantitative real time PCR (QRT-PCR) and western blot were performed to determine the expression levels of IRF2, INPP4B and autophagy-related markers in AML cell...

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PMID: 30876449
DOI: 10.1186/s40659-019-0218-7

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