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Article

Research progress on the PI3K/AKT signaling pathway in gynecological cancer (Review)

3 Apr 2019

Abstract excerpt

The phosphatidylinositol 3‑kinase (PI3K)/protein kinase B (AKT) signaling pathway is involved in the regulation of multiple cellular physiological processes by activating downstream corresponding effector molecules, which serve an important role in the cell cycle, growth and proliferation. This is a common phenomenon; overactivation of the pathway is present in human malignancies and has been implicated in cancer...

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PMID: 30942405
DOI: 10.3892/mmr.2019.10121

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