Article
Evaluation of very early-onset inflammatory bowel disease.
Current opinion in gastroenterology - 1 Nov 2020
de Mesquita Mirjam Bueno, Shouval Dror S
Abstract excerpt
PURPOSE OF REVIEW: Very early-onset inflammatory bowel disease (VEO-IBD) is a rare presentation defined as onset of intestinal inflammation at the age of <6 years. Some of these young children develop IBD because of inherent defects in immune or epithelial cell function resulting from deleterious mutations in genes involved in mucosal homeostasis. Here, we provide an overview of the clinical, genetic and...
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