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Article

A mycobacterium ESX-1-secreted virulence factor with unique requirements for export.

PLoS pathogens - 3 Aug 2007

McLaughlin Bryant, Chon Janet S, MacGurn Jason A, Carlsson Fredric, Cheng Terri L, Cox Jeffery S, Brown Eric J

Abstract excerpt

Specialized secretion systems of pathogenic bacteria commonly transport multiple effectors that act in concert to control and exploit the host cell as a replication-permissive niche. Both the Mycobacterium marinum and the Mycobacterium tuberculosis genomes contain an extended region of difference 1 (extRD1) locus that encodes one such pathway, the early secretory antigenic target 6 (ESAT-6) system 1 (ESX-1)...

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Identifiers

PMID: 17676952
DOI: 10.1371/journal.ppat.0030105
PMCID: PMC1937011

Genes

CFP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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A mycobacterium ESX-1-secreted virulence factor with unique requirements for export.PMID 17676952Read ↗

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