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Article

Spectrum of somatic EGFR, KRAS, BRAF, PTEN mutations and TTF-1 expression in Brazilian lung cancer patients.

Genetics research - 1 Jan 2014

Carneiro Juliana G, Couto Patricia G, Bastos-Rodrigues Luciana, Bicalho Maria Aparecida C, Vidigal Paula V, Vilhena Alyne, Amaral Nilson F, Bale Allen E, Friedman Eitan, De Marco Luiz

Abstract excerpt

Lung cancer is the leading global cause of cancer-related mortality. Inter-individual variability in treatment response and prognosis has been associated with genetic polymorphisms in specific genes: EGFR, KRAS, BRAF, PTEN and TTF-1. Somatic mutations in EGFR and KRAS genes are reported at rates of 15-40% in non-small cell lung cancer (NSCLC) in ethnically diverse populations. BRAF and PTEN are commonly mutated...

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Source

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Identifiers

PMID: 24594201
DOI: 10.1017/S0016672314000032
PMCID: PMC7045132

Genes

EGFR
PTEN
BRAF
KRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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