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Article

Fibroblast Primary Cilia Are Required for Cardiac Fibrosis

1 Mar 2019

Abstract excerpt

BACKGROUND: The primary cilium is a singular cellular structure that extends from the surface of many cell types and plays crucial roles in vertebrate development, including that of the heart. Whereas ciliated cells have been described in developing heart, a role for primary cilia in adult heart has not been reported. This, coupled with the fact that mutations in genes coding for multiple ciliary proteins...

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PMID: 30818997
DOI: 10.1161/circulationaha.117.028752

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