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Article

Early onset preeclampsia in a model for human placental trophoblast

20 Feb 2019

Abstract excerpt

We describe a model for early onset preeclampsia (EOPE) that uses induced pluripotent stem cells (iPSCs) generated from umbilical cords of EOPE and control (CTL) pregnancies. These iPSCs were then converted to placental trophoblast (TB) representative of early pregnancy. Marker gene analysis indicated that both sets of cells differentiated at comparable rates. The cells were tested for parameters disturbed in...

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PMID: 30787190
DOI: 10.1073/pnas.1816150116

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