Back to search

Article

Over-expressed KRT8 in the cytotrophoblast shell promotes the development of preeclampsia

2025-01-09

Abstract excerpt

Preeclampsia is a “placenta-derived disorder” characterized disease, which remains a major unaddressed public health problem. The differentiation and development of cytotrophoblasts and extravillous trophoblasts are two crucial processes, which are tightly regulated. And any abnormal regulation can lead to the occurrence of pregnancy-related diseases such as preeclampsia. In this article, we performed Spatial tran...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
ea428d07-38b5-5b30-94f8-dc47f6dc86c4
DOI
10.1101/2025.01.06.25320086
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Over-expressed KRT8 in the cytotrophoblast shell promotes the development of preeclampsiaDOI 10.1101/2025.01.06.25320086
Single-cell transcriptional profiling reveals cellular and molecular divergence in human maternal-fetal interfaceSemantic proximity
Single-cell transcriptional profiling reveals cellular and molecular divergence in human maternal–fetal interfaceSemantic proximity
Trophoblast Cell Subtypes and Dysfunction in the Placenta of Individuals with Preeclampsia Revealed by Single-Cell RNA SequencingSemantic proximity
Single-cell RNA-seq reveals developmental deficiencies in both the placentation and the decidualization in women with late-onset preeclampsiaSemantic proximity
PLAC8, a new marker for human interstitial extravillous trophoblast cells, promotes their invasion and migrationSemantic proximity
Dissecting human placental cells heterogeneity in preeclampsia and gestational diabetes using single-cell sequencingSemantic proximity
Human Placental Endothelial Cell and Trophoblast Heterogeneity and Differentiation Revealed by Single-Cell RNA SequencingSemantic proximity
Hypoxic Microenvironment Promotes PTBP1 Lactonization and IGF2BP2 Read Defects Mediate the Development of PreeclampsiaSemantic proximity
A Multiomics, Spatiotemporal, and Single Cell Atlas for Mapping Cell-Type-Specific Dysregulation at the Maternal-Fetal InterfaceSemantic proximity
Placenta-Specific Genes, Their Regulation During Villous Trophoblast Differentiation and Dysregulation in Preterm PreeclampsiaSemantic proximity
Cross‐Species Insights into Trophoblast Invasion During Placentation Governed by Immune‐Featured Trophoblast CellsSemantic proximity
Single-Cell RNA Sequencing Reveals Regulatory Mechanism for Trophoblast Cell-Fate Divergence in Human Peri-Implantation EmbryoSemantic proximity
Select a neighboring publication to make it the new centre.