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Article

Epigenetically Altered T Cells Contribute to Lupus Flares

5 Feb 2019

Abstract excerpt

Lupus flares when genetically predisposed people encounter exogenous agents such as infections and sun exposure and drugs such as procainamide and hydralazine, but the mechanisms by which these agents trigger the flares has been unclear. Current evidence indicates that procainamide and hydralazine, as well as inflammation caused by the environmental agents, can cause overexpression of genes normally silenced by...

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PMID: 30764520
DOI: 10.3390/cells8020127

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