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Article

Environmental exposures, epigenetic changes and the risk of lupus.

Lupus - 1 May 2014

Somers E C, Richardson B C

Abstract excerpt

A dose-dependent combination of environmental exposures, estrogenic hormones and genetic predisposition is thought to be required for lupus to develop and flare, but how the environment modifies the immune system in genetically predisposed people is unclear. Current evidence indicates that environmental agents that inhibit DNA methylation can convert normal antigen-specific CD4+ T lymphocytes into autoreactive,...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Lupus Erythematosus, Systemic

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Source

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Identifiers

PMID: 24763540
DOI: 10.1177/0961203313499419
PMCID: PMC4000546

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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