Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Generation of Infectious Recombinant Human Rotaviruses from Just 11 Cloned cDNAs Encoding the Rotavirus Genome

7 Feb 2019

Abstract excerpt

Human group A rotavirus (HuRVA) is a leading pathogen causing severe diarrhea in young children worldwide. In this paper, we describe the generation of recombinant HuRVA (strain KU) from only 11 cloned cDNAs encoding the HuRVA genome by reverse genetics. The growth properties of the recombinant HuRVA were similar to those of the parental RVA, providing a powerful tool for better understanding of HuRVA replication...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Animal Virus Infections Studies
Share to Viral gastroenteritis research and epidemiology
Share to Virus-based gene therapy research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 30728265
DOI: 10.1128/jvi.02207-18

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Generation of Infectious Recombinant Human Rotaviruses from Just 11 Cloned cDNAs Encoding the Rotavirus GenomePMID 30728265Read ↗

An Optimized Reverse Genetics System Suitable for Efficient Recovery of Simian, Human, and Murine-Like RotavirusesSemantic proximity Read ↗

Reverse Genetics System for a Human Group A Rotavirus.Semantic proximity Read ↗

Reverse genetics system for introduction of site-specific mutations into the double-stranded RNA genome of infectious rotavirus.Semantic proximity Read ↗

Generation of Recombinant Rotaviruses Expressing Human Norovirus Capsid ProteinsSemantic proximity Read ↗

Establishment of a Reverse Genetics System for Rotavirus Vaccine Strain LLR and Developing Vaccine Candidates Carrying VP7 Gene Cloned From Human Strains Circulating in China.Semantic proximity Read ↗

Simplified Reverse Genetics Method to Recover Recombinant Rotaviruses Expressing Reporter ProteinsSemantic proximity Read ↗

Rearranged Genomic RNA Segments Offer a New Approach to the Reverse Genetics of RotavirusesSemantic proximity Read ↗

Reverse Genetics Approach for Developing Rotavirus Vaccine Candidates Carrying VP4 and VP7 Genes Cloned from Clinical Isolates of Human Rotavirus.Semantic proximity Read ↗

Establishment of a reverse genetics system for rotavirus vaccine strain LLR and developing vaccine candidates carrying VP7 gene cloned from human strains circulating in ChinaSemantic proximity Read ↗

Generation of single-round infectious rotavirus with a mutation in the intermediate capsid protein VP6.Semantic proximity Read ↗

Generation of Recombinant Rotaviruses Expressing Human Norovirus Capsid ProteinsSemantic proximity Read ↗

FAST Proteins: Development and Use of Reverse Genetics Systems for Reoviridae VirusesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.