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Cystathionine as a marker for 1p/19q codeleted gliomas by in vivo magnetic resonance spectroscopy

30 Jan 2019

Abstract excerpt

BACKGROUND: Codeletion of chromosome arms 1p and 19q (1p/19q codeletion) highly benefits diagnosis and prognosis in gliomas. In this study, we investigated the effect of 1p/19q codeletion on cancer cell metabolism and evaluated possible metabolic targets for tailored therapies. METHODS: We combined in vivo 1H (proton) magnetic resonance spectroscopy (MRS) measurements in human gliomas with the analysis of a...

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PMID: 30726924
DOI: 10.1093/neuonc/noz031

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