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Article

Characterization of genomic alterations in primary central nervous system lymphomas.

Journal of neuro-oncology - 1 Dec 2018

Zorofchian Soheil, El-Achi Hanadi, Yan Yuanqing, Esquenazi Yoshua, Ballester Leomar Y

Abstract excerpt

PURPOSE: Primary central nervous system lymphoma (PCNSL) is a non-Hodgkin lymphoma that affects the central nervous system (CNS). Although previous studies have reported the most common mutated genes in PCNSL, including MYD88 and CD79b, our understanding of genetic characterizations in primary CNS lymphomas is limited. The aim of this study was to perform a retrospective analysis investigating the most frequent...

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Aged
Aged, 80 and over
Central Nervous System Neoplasms
Frameshift Mutation
High-Throughput Nucleotide Sequencing

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutation, Missense

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Identifiers

PMID: 30171453
DOI: 10.1007/s11060-018-2990-6

Genes

MYD88
BCL6
IGH

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