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Article

Experimental microdissection enables functional harmonisation of pancreatic cancer subtypes

18 Jan 2019

Abstract excerpt

OBJECTIVE: attempts at expression-based molecular classification. The goal of this work is to profile purified samples of human PDA epithelium and stroma and examine their respective contributions to gene expression in bulk PDA samples. DESIGN: We used laser capture microdissection (LCM) and RNA sequencing to profile the expression of 60 matched pairs of human PDA malignant epithelium and stroma samples. We then...

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PMID: 30658994
DOI: 10.1136/gutjnl-2018-317706

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