Article

The Limits of Molecular Signatures for Pancreatic Ductal Adenocarcinoma Subtyping

2022-05-16

Abstract excerpt

<h4>ABSTRACT</h4> Molecular signatures have been suggested as biomarkers to classify pancreatic ductal adenocarcinoma (PDAC) into two, three or four subtypes. Since the robustness of existing signatures is controversial, we performed a systematic evaluation of three established signatures for PDAC stratification across eight publicly available datasets. Clustering revealed inconsistency of subtypes across indepen...

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Literature Corpus work: 1fc5367d-365e-58ae-b56b-8e4036268a8e
DOI: 10.1101/2022.05.16.491983

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