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Article

Epigenetic regulation of the human ATP2A3 gene promoter in gastric and colon cancer cell lines

18 Jan 2019

Abstract excerpt

concentration, regulating various cellular processes including cell growth. ATP2A3 gene transcriptional down-regulation has been reported in gastric and colon cancer, but there is still a lack of understanding about the epigenetic processes regulating its transcription. In this work, we report that butyrate, trichostatin A, and 5-azacytidine treatments increase SERCA3 expression, increased apoptosis, and...

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PMID: 30657210
DOI: 10.1002/mc.22978

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