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Induction of cell differentiation activates transcription of the Sarco/Endoplasmic Reticulum calcium‐ATPase 3 gene (<i>ATP2A3</i>) in gastric and colon cancer cells

19 Jul 2016

Abstract excerpt

concentrations to regulate various cellular processes including cell growth. Previous studies have reported a downregulation of SERCA3 protein expression in gastric and colon cancer cell lines and showed that in vitro cell differentiation increases its expression. However, little is known about the transcriptional mechanisms and transcription factors that regulate SERCA3 expression in epithelial cancer cells. In...

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PMID: 27433831
DOI: 10.1002/mc.22529

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