Article
Expression of endomembrane calcium pumps in colon and gastric cancer cells. Induction of SERCA3 expression during differentiation.
The Journal of biological chemistry - 19 Jul 2002
Gélébart Pascal, Kovács Tunde, Brouland Jean-Philippe, van Gorp Roosje, Grossmann Johannes, Rivard Nathalie, Panis Yves, Martin Virginie, Bredoux Raymonde, Enouf Jocelyne, Papp Béla
Abstract excerpt
Calcium mobilization from the endoplasmic reticulum (ER) into the cytosol is a key component of several signaling networks controlling tumor cell growth, differentiation, or apoptosis. Sarco/endoplasmic reticulum calcium transport ATPases (SERCA-type calcium pumps), enzymes that accumulate calcium in the ER, play an important role in these phenomena. We report that SERCA3 expression is significantly reduced or...
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