Back to search

Article

The Warburg Effect Hallmark in Nasopharyngeal Carcinoma: Stage-Specific Up-Regulation of LDHA, GAPDH, CS, CYC, MRPL3, and TIMMDC1 Drives a Hybrid Glycolysis/OXPHOS Profile during Regional Progression

2026-07-03

Abstract excerpt

<title>Abstract</title> <p> <bold>Background</bold> : Nasopharyngeal carcinoma (NPC) is an aggressive epithelial malignancy with distinct clinical dynamics across its developmental stages. While metabolic reprogramming is a recognized hallmark of cancer, the stage-specific activation of aerobic glycolysis—the Warburg effect—and its exact molecular indicators during NPC progression remain to be fully mapped. Thi...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
ca29f329-918d-585e-a61c-a8b43ea9871c
DOI
10.21203/rs.3.rs-10225258/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
The Warburg Effect Hallmark in Nasopharyngeal Carcinoma: Stage-Specific Up-Regulation of LDHA, GAPDH, CS, CYC, MRPL3, and TIMMDC1 Drives a Hybrid Glycolysis/OXPHOS Profile during Regional ProgressionDOI 10.21203/rs.3.rs-10225258/v1
The role and mechanism of aerobic glycolysis in nasopharyngeal carcinomaSemantic proximity
Metabolic expression profiling analysis reveals pyruvate-mediated EPHB2 upregulation promotes lymphatic metastasis in head and neck squamous cell carcinomasSemantic proximity
A Novel Glycolysis Evaluation System for Stratified Management and Individualized Treatment of OSCC PatientsSemantic proximity
An Epigenetic Regulatory Hubin Nasopharyngeal Carcinoma: Coordinated Action of DNMT1, EZH2, HDAC2, SMARCA4, BRD4, and H19during Regional ProgressionSemantic proximity
Single-Cell Atlas Identifies TUBB2B+ Epithelial Subpopulations as Hubs of Methionine Metabolism in Nasopharyngeal CarcinomaSemantic proximity
Revisiting the biological role of the Warburg effect: Evolving perspectives on cancer metabolismSemantic proximity
Multi-level Regulatory Roles of Lactate Metabolism Gene Network in Oral Cancer: Machine Learning InsightsSemantic proximity
Cancer Cell Metabolism Reprogramming and Its Potential Implications on Therapy in Squamous Cell Carcinoma of the Head and Neck: A ReviewSemantic proximity
Identification of a metabolic signature genes predicting overall survival for Head and neck squamous cell carcinomaSemantic proximity
Micromanaging aerobic respiration and glycolysis in cancer cellsSemantic proximity
Targeting the Warburg Effect in Anaplastic and Poorly Differentiated Thyroid Carcinoma: Metabolic Vulnerabilities and Therapeutic OpportunitiesSemantic proximity
Stage-Independent Downregulation of the GSTA1/GSTA3 Gene Cluster on Chromosome 6p12 as a Metabolic Hallmark of Nasopharyngeal CarcinomaSemantic proximity
Select a neighboring publication to make it the new centre.