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Article

Malaria-specific Type 1 regulatory T cells are more abundant in first pregnancies and associated with placental malaria

25 Aug 2023

Abstract excerpt

Background Malaria in pregnancy (MIP) causes higher morbidity in primigravid compared to multigravid women; however, the correlates and mechanisms underlying this gravidity-dependent protection remain incompletely understood. We aimed to compare the cellular immune response between primigravid and multigravid women living in a malaria-endemic region and assess for correlates of protection against MIP. Methods We...

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PMID: 37634385
DOI: 10.1016/j.ebiom.2023.104772

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