Article
A novel approach to studying early knee osteoarthritis illustrates that bilateral medial tibiofemoral osteoarthritis is a heritable phenotype: an offspring study.
Rheumatology international - 1 Jun 2022
Lo Grace H, Richard Michael J, Cauley Jane A, Driban Jeffrey B, Strayhorn Michael, MacKay James, Harkey Matthew S, McAlindon Timothy E, Jansen Mary, Green Stephanie, White Donna L, Kwoh C Kent
Abstract excerpt
To assess the potential of studying offspring of people with and without knee osteoarthritis to understand the risk factors and heritability for knee osteoarthritis. We selected two groups of Osteoarthritis Initiative (OAI) participants from one clinical site: (1) participants with bilateral radiographic medial tibiofemoral osteoarthritis and (2) those without tibiofemoral osteoarthritis. We then invited...
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