Article
Genetics of osteoarthritis.
Annals of the rheumatic diseases - 1 Sept 1996
Cicuttini F M, Spector T D
Abstract excerpt
The available evidence suggests that genetic factors have a major role in osteoarthritis. It has been believed for over 50 years that a strong genetic component to certain forms of osteoarthritis is present. This genetic influence has now been estimated to be up to 65% in a recent twin study. The nature of the genetic influence in osteoarthritis is speculative and may involve either a structural defect (that is,...
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