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Placental Origins of Preeclampsia: Insights from Multi-Omic Studies

28 Aug 2024

Abstract excerpt

Preeclampsia (PE) is a major cause of maternal and neonatal morbidity and mortality worldwide, with the placenta playing a central role in disease pathophysiology. This review synthesizes recent advancements in understanding the molecular mechanisms underlying PE, focusing on placental genes, proteins, and genetic variants identified through multi-omic approaches. Transcriptomic studies in bulk placental tissue...

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PMID: 39273292
DOI: 10.3390/ijms25179343

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