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Article

Circulating tumor DNA alterations in patients with metastatic castration‐resistant prostate cancer

8 Jan 2019

Abstract excerpt

BACKGROUND: Because cell-free DNA (cfDNA) analysis facilitates the noninvasive genomic profiling of metastatic castration-resistant prostate cancer (mCRPC), the authors evaluated the association between cfDNA alterations and outcomes and evolution with therapy. METHODS: Patients with mCRPC underwent cfDNA genomic profiling using Guardant360, which examines major cancer-associated genes. Clinical factors, therapy...

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PMID: 30620391
DOI: 10.1002/cncr.31959

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