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Article

In vivo targeting of DNA vaccines to dendritic cells using functionalized gold nanoparticles

10 Dec 2018

Abstract excerpt

The clinical success of dendritic cell (DC)-based genetic immunization remains critically dependent on the availability of effective and safe nano-carriers for targeting antigen-encoded DNA vaccines to DCs, the most potent antigen-presenting cells in the human body in vivo. Recent studies revealed the efficacies of mannose receptor-mediated in vivo DC-targeted genetic immunization by liposomal DNA vaccine...

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PMID: 30601510
DOI: 10.1039/c8bm01272e

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