Article
Cytokine induced killer cells-assisted delivery of chlorin e6 mediated self-assembled gold nanoclusters to tumors for imaging and immuno-photodynamic therapy.
Biomaterials - 1 Jul 2018
Xia Fangfang, Hou Wenxiu, Liu Yanlei, Wang Wentao, Han Yu, Yang Meng, Zhi Xiao, Li Chenlu, Qi Daizong, Li Tianliang, Martinez de la Fuente Jesus, Zhang Chunlei, Song Jie, Cui Daxiang
Abstract excerpt
The cytotoxicity and unique tumor-tropic properties of cytokine-induced killer (CIK) cells render them promising in the field of cancer immunotherapy and delivery systems. Here, we report a novel and facile approach to assemble gold nanoclusters (GNCs) into stable and monodispersed nanoparticles (NPs) using Chlorin e6 (Ce6) molecules. Notably, the fluorescence intensity of the GNCs-Ce6 NPs was about 4.5 folds...
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