Article
Haptoglobin 2 Allele is Associated With Histologic Response to Vitamin E in Subjects With Nonalcoholic Steatohepatitis.
Journal of clinical gastroenterology - 1 Jan 2019
Banini Bubu A, Cazanave Sophie C, Yates Katherine P, Asgharpour Amon, Vincent Robert, Mirshahi Faridoddin, Le Peter, Contos Melissa J, Tonascia James, Chalasani Naga P, Kowdley Kris V, McCullough Arthur J, Behling Cynthia A, Schwimmer Jeffrey B, Lavine Joel E, Sanyal Arun J
Abstract excerpt
BACKGROUND: Haptoglobin (Hp) genotype has been linked to oxidative stress and cardiovascular outcomes in response to vitamin E (VitE) among patients with diabetes mellitus. Its effect on histologic response to VitE in nonalcoholic steatohepatitis (NASH) is unknown. GOALS: Our objective was to determine if Hp genotype associates with response to VitE in patients with NASH. STUDY: A post hoc analysis of 228...
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