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Article

MPK‐1/ERK is required for the full activity of resveratrol in extended lifespan and reproduction

21 Dec 2018

Abstract excerpt

Resveratrol (RSV) extends the lifespan of various organisms through activation of sirtuin. However, whether RSV-mediated longevity is entirely dependent upon sirtuin is still controversial. Thus, understanding additional mechanisms concerning the genetic requirements for the biological activity of RSV needs to be clarified to utilize the beneficial effects of RSV. In this study using Caenorhabditis elegans as a...

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PMID: 30575269
DOI: 10.1111/acel.12867

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