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Article

Restriction Factors: From Intrinsic Viral Restriction to Shaping Cellular Immunity Against HIV-1

6 Dec 2018

Abstract excerpt

Antiviral restriction factors are host cellular proteins that constitute a first line of defense blocking viral replication and propagation. In addition to interfering at critical steps of the viral replication cycle, some restriction factors also act as innate sensors triggering innate responses against infections. Accumulating evidence suggests an additional role for restriction factors in promoting antiviral...

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Identifiers

PMID: 30574147
DOI: 10.3389/fimmu.2018.02876

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