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Anti-HIV Factors: Targeting Each Step of HIV's Replication Cycle

4 Mar 2016

Abstract excerpt

BACKGROUND: Similar to other animal viruses, HIV-1 relies on the contributions of the cellular machinery to ensure efficient virus propagation. However, human cells have evolved refined mechanisms to block key steps of the virus life-cycle, thereby suppressing viral replication. These cellular proteins are generally known as restriction factors, and they provide an early antiviral defense. So far, five potent...

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PMID: 26957194
DOI: 10.2174/1570162x14999160224094621

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