HIV Restriction Factors and Mechanisms of Evasion.

doi:10.1101/cshperspect.a006940

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Article

HIV Restriction Factors and Mechanisms of Evasion.

Cold Spring Harbor perspectives in medicine - 1 May 2012

Malim Michael H, Bieniasz Paul D

Abstract excerpt

Retroviruses have long been a fertile model for discovering host-pathogen interactions and their associated biological principles and processes. These advances have not only informed fundamental concepts of viral replication and pathogenesis but have also provided novel insights into host cell biology. This is illustrated by the recent descriptions of host-encoded restriction factors that can serve as effective...

Topics

APOBEC Deaminases
Antigens, CD
Antiviral Restriction Factors
Carrier Proteins
Cytidine Deaminase
Cytosine Deaminase
GPI-Linked Proteins
Genes, vif
HIV Infections
HIV-1
Host-Pathogen Interactions

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Humans

Mutation

Tripartite Motif Proteins

Ubiquitin-Protein Ligases

Viral Regulatory and Accessory Proteins

Virus Replication

Source

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Identifiers

PMID: 22553496
DOI: 10.1101/cshperspect.a006940
PMCID: PMC3331687

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