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SOX9 regulated matrix proteins are increased in patients serum and correlate with severity of liver fibrosis

11 Dec 2018

Abstract excerpt

Extracellular matrix (ECM) deposition and resultant scar play a major role in the pathogenesis and progression of liver fibrosis. Identifying core regulators of ECM deposition may lead to urgently needed diagnostic and therapetic strategies for the disease. The transcription factor Sex determining region Y box 9 (SOX9) is actively involved in scar formation and its prevalence in patients with liver fibrosis...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 30559459
DOI: 10.1038/s41598-018-36037-4

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